← All simulations

Circulation and blood pressure

This model follows the circulation chapter's blood pressure equations: cardiac output supplies the beat, while total peripheral resistance determines how much pressure remains between beats. Compare resting and exercise conditions, then change one variable at a time.

Read the Circulation chapter

Live model

Blood Pressure Equation Explorer

Follow one pressure wave between heartbeats. During diastole, pressure runs off through the resistance network. During systole, stroke volume adds a new pressure pulse.

Try a comparison:Compare higher HR and SV with lower TPR.

The equation is normalized to a resting pressure wave near 120/80 mmHg. The model uses arterial resistance and compliance to determine runoff between beats.

Blood pressure

122/82

Pulse pressure

40 mmHg

Mean pressure

95 mmHg

Cardiac output

4.9 L/min

One cardiac cycle

Pressure rises with ejection, then runs off during diastole

0.86 s
Arterial pressure over one cardiac cyclePressure rises rapidly to systolic pressure, briefly notches as ejection ends, and decays to diastolic pressure before the next heartbeat.50100150SBP 122DBP 82
rapid systolic upstrokediastolic runoff to the next beat

Diastolic runoff

40 mmHg

Read the change

Adjust HR, stroke volume, or TPR to see whether runoff or the systolic pulse dominates.

During diastole

Pressure runs off through TPR

Higher resistance leaves more pressure in the arteries before the next beat. Lower resistance lets pressure fall faster.

During systole

SBP = DBP + pulse pressure

The next stroke volume creates the pressure jump. A larger stroke volume generally widens pulse pressure.

Teaching model, not a clinical calculator. Real arterial pressure depends on distributed vascular beds, wave reflections, contractility, and changing vessel properties that are simplified here.